Evidence-based: Creatine Effectiveness

Evidence-based: Creatine Effectiveness

Creatine is a popular supplement among athletes, bodybuilders, and fitness enthusiasts. It is a naturally occurring substance found in our muscles, and it is also present in foods such as meat and fish. Creatine is known for its ability to increase strength, power, and muscle mass, and it has been studied extensively over the past few decades. In this article, we will explore the evidence behind creatine effectiveness and its benefits and risks.

What is creatine?

Creatine is a compound made up of three amino acids: arginine, glycine, and methionine. It is synthesized in our bodies and is also obtained from dietary sources such as meat and fish. Creatine is stored in our muscles in the form of phosphocreatine, which is used to produce energy during high-intensity exercise.

Creatine and muscle performance

Creatine has been shown to increase muscle strength and power, particularly during high-intensity exercise such as weightlifting and sprinting. This is because creatine increases the amount of phosphocreatine in our muscles, which allows us to produce more energy during short bursts of activity. Several studies have shown that creatine supplementation can lead to significant increases in muscle strength and power, particularly in activities that require short bursts of energy, such as weightlifting and sprinting. A meta-analysis of 22 studies found that creatine supplementation increased strength by an average of 8% and power by an average of 14%.

Creatine and muscle mass

Creatine has also been shown to increase muscle mass, particularly when combined with resistance training. This is because creatine supplementation can lead to increased water content in our muscles, which can contribute to muscle hypertrophy (growth). Several studies have shown that creatine supplementation can lead to significant increases in muscle mass, particularly when combined with resistance training. A meta-analysis of 18 studies found that creatine supplementation increased muscle mass by an average of 0.5 kg (1.1 lbs) over a period of 4-12 weeks.

Creatine and endurance performance

While creatine is primarily known for its benefits in high-intensity exercise, it may also have benefits for endurance performance. One study found that creatine supplementation improved running performance in trained runners by 2-3%. However, the evidence for creatine's benefits in endurance performance is mixed, with some studies showing no effect. More research is needed to determine the extent of creatine's benefits for endurance performance.

Creatine and cognitive function

There is some evidence to suggest that creatine supplementation may have benefits for cognitive function, particularly in tasks that require short-term memory and intelligence. One study found that creatine supplementation improved working memory and intelligence in vegetarians, who have lower levels of creatine in their brains compared to meat-eaters. However, more research is needed to determine the extent of creatine's benefits for cognitive function.

Risks of creatine supplementation

Creatine supplementation is generally safe when taken in recommended doses. However, there are some potential risks to be aware of. One potential risk is dehydration, as creatine can increase water retention in our muscles. It is important to drink plenty of water when taking creatine to prevent dehydration. Another potential risk is kidney damage, although this is rare and generally only occurs in people with pre-existing kidney conditions. Finally, some people may experience gastrointestinal discomfort, such as bloating and diarrhea, when taking creatine. This can often be avoided by taking creatine with food and/or using a lower dose.

Conclusion

Creatine is a popular supplement with a lot of evidence behind its effectiveness for increasing muscle strength, power, and mass. It may also have benefits for endurance performance and cognitive function, although more research is needed in these areas. Creatine supplementation is generally


reference
Rawson ES, Volek JS. Effects of creatine supplementation and resistance training on muscle strength and weightlifting performance. J Strength Cond Res. 2003 Nov;17(4):822-31. doi: 10.1519/1533-4287(2003)017(0822:eocsar)2.0.co;2. PMID: 14636102. Kreider RB. Effects of creatine supplementation on performance and training adaptations. Mol Cell Biochem. 2003 Feb;244(1-2):89-94. doi: 10.1023/a:1022465203458. PMID: 12701815. Antonio J, Ciccone V. The effects of pre versus post workout supplementation of creatine monohydrate on body composition and strength. J Int Soc Sports Nutr. 2013 Aug 6;10(1):36. doi: 10.1186/1550-2783-10-36. PMID: 23919405; PMCID: PMC3754093. Branch JD. Effect of creatine supplementation on body composition and performance: a meta-analysis. Int J Sport Nutr Exerc Metab. 2003 Mar;13(2):198-226. doi: 10.1123/ijsnem.13.2.198. PMID: 12945830. Mujika I, Padilla S. Creatine supplementation as an ergogenic aid for sports performance in highly trained athletes: a critical review. Int J Sports Med. 1997 Oct;18(7):491-6. doi: 10.1055/s-2007-972658. PMID: 9414070. McMorris T, Mielcarz G, Harris RC, Swain JP, Howard A. Creatine supplementation and cognitive performance in elderly individuals. Aging Neuropsychol Cogn. 2007 Jul;14(4):517-28. doi: 10.1080/13825580701388843. PMID: 17729054. Rae C, Digney AL, McEwan SR, Bates TC. Oral creatine monohydrate supplementation improves brain performance: a double--blind, placebo-controlled, cross-over trial. Proc Biol Sci. 2003 Oct 22;270(1529):2147-50. doi: 10.1098/rspb.2003.2492. PMID: 14561278; PMCID: PMC1691485. Cooper R, Naclerio F, Allgrove J, Jimenez A. Creatine supplementation with specific view to exercise/sports performance: an update. J Int Soc Sports Nutr. 2012 Jul 20;9(1):33. doi: 10.1186/1550-2783-9-33. PMID: 22817979; PMCID: PMC3407788. Bemben MG, Lamont HS. Creatine supplementation and exercise performance: recent findings. Sports Med. 2005;35(2):107-25. doi: 10.2165/00007256-200535020-00002. PMID: 15707376. Poortmans JR, Francaux M. Adverse effects of creatine supplementation: fact or fiction? Sports Med. 2000 Sep;30(3):155-70. doi: 10.2165/00007256-200030030-00002. PMID: 10999421.


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